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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FOXO4 All Species: 7.58
Human Site: S244 Identified Species: 18.52
UniProt: P98177 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P98177 NP_005929.2 505 53684 S244 K W S G S P C S R N R E E A D
Chimpanzee Pan troglodytes XP_001135016 505 53494 S244 K W S G S P C S R N R E E A D
Rhesus Macaque Macaca mulatta XP_001088437 860 91177 S508 P A S P G S H S N D D F D N W
Dog Lupus familis XP_549066 509 54008 R248 W S G S P C S R N R E E A D V
Cat Felis silvestris
Mouse Mus musculus Q9WVH3 505 53631 P244 K W S S S P C P R N R E E A D
Rat Rattus norvegicus NP_001100413 505 53925 P244 K W S S S P C P R N R E E A D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426261 470 50115 L219 T V T E E L E L I D G L N L M
Frog Xenopus laevis Q6EUW1 657 70366 S285 G S P T S R S S D K L D T W T
Zebra Danio Brachydanio rerio XP_692168 613 64303 A330 G G A S P S M A P P A P P Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95V55 613 67394 Y334 S Q P P P P P Y Q P P Q H Q Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 31.9 92.1 N.A. 88.5 88.3 N.A. N.A. 53.4 37.9 44.2 N.A. 28.5 N.A. N.A. N.A.
Protein Similarity: 100 98.8 42 95 N.A. 93 92.4 N.A. N.A. 63.5 52 56.2 N.A. 43.5 N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 6.6 N.A. 86.6 86.6 N.A. N.A. 0 13.3 0 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 6.6 N.A. 86.6 86.6 N.A. N.A. 13.3 20 13.3 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 0 0 10 0 0 10 0 10 40 0 % A
% Cys: 0 0 0 0 0 10 40 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 20 10 10 10 10 40 % D
% Glu: 0 0 0 10 10 0 10 0 0 0 10 50 40 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 20 10 10 20 10 0 0 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 40 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 0 10 0 0 10 10 0 10 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 20 40 0 0 10 10 0 % N
% Pro: 10 0 20 20 30 50 10 20 10 20 10 10 10 0 10 % P
% Gln: 0 10 0 0 0 0 0 0 10 0 0 10 0 20 10 % Q
% Arg: 0 0 0 0 0 10 0 10 40 10 40 0 0 0 0 % R
% Ser: 10 20 50 40 50 20 20 40 0 0 0 0 0 0 0 % S
% Thr: 10 0 10 10 0 0 0 0 0 0 0 0 10 0 10 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 10 40 0 0 0 0 0 0 0 0 0 0 0 10 10 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _